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By slowing digestion and signaling fullness to the brain, GLP-1 may play a supporting role in weight management
The core domain of the HCV IRES contains a four-way helical Holliday junction that is integrated within a predicted pseudoknot
To determine the solution structural model of the p53 TAD2 -FOXO4-DRI complex using NMR spectroscopy, we recorded several sets of NMR experiments on two types of complexes: 13 C, 15 N-labelled p53 TAD2 -FOXO4-DRI and 13 C, 15 N-labelled FOXO4-LRI D -p53 TAD2 (see methods)
GLP-1 receptor agonists are licensed in the UK for type 2 diabetes and weight management within specialist services, following NICE guidance
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