However, at baseline the per-protocol adjusted groups did not differ significantly in age, sex, BMI, pubertal status or glucose tolerance

Heres your action plan: Step 1: Stop the medication immediately As soon as you see that positive pregnancy test Dont wait for a doctors appointment to stop Dont take one more dose while you figure things out Stop today Step 2: Call your prescribing doctor The doctor who prescribed your GLP-1 needs to know Theyll document when you stopped and your last dose They may need to transition you to alternative medications (if using GLP-1 for diabetes) Step 3: Contact your OB/GYN or schedule first prenatal visit Schedule appointment within 1-2 weeks Bring documentation: medication name, dose, start date, last injection date Your OB/GYN will establish appropriate monitoring plan They may recommend earlier or additional ultrasounds Step 4: Dont panicseriously These medications havent been clearly linked to birth defects in the limited human data we have so far, but we also dont have enough high-quality studies to say theyre definitely safe
Lin L, Xu X, Yu Y, et al
Cytotoxic chemotherapy and several targeted agents induce dose-dependent systemic toxicities, such as myelosuppression, hepatic and renal injury, and gastrointestinal adverse events, which limit the dose intensity and duration that patients can tolerate [5, 6]
Up to 20% of (specialty) drugs can be cost-saving, that is, for each dollar spent payers can actually save money over a given period of time in terms of lower downstream costs
Theyll likely have you wait at least 2 weeks between treatment with Contrave and an MAOI