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Additionally, the majority of studies did not report adverse events stratified by age within adults, thus preventing subgroup analyses comparing adult and elderly subjects

the placebo group (74.2% and 47.9%, respectively), which contributed to a discontinuation rate of 7%

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Importance of Long-Term Evaluation of Adverse Events The results on the long-term safety are important since it was initially a concern that DPP-4 inhibition may be associated with adverse events

Das KS, Balakrishnan V, Mukherjee S, Vasudevan DM (2008) Evaluation of blood oxidative stress-related parameters in alcoholic liver disease and non-alcoholic fatty liver disease

These medications require proper medical supervision and provider evaluation before starting therapy