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Sphingolipid metabolites in inflammatory disease

Around the same time, I think you remember that all of pharma was interested in obesity in the early 90s, everyone wanted to do diabetes as well as obesity, but they were separate teams and they all wanted to do small molecules, but it just happens to be so that the best idea we could find at that time was actually GLP-1, because we actually had clinical data relatively early that GLP-1 was a really good candidate as a treatment for diabetes because of the glucose sensitivity of the actions

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especially during the pandemic, said Bates

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Lower Nr5a2 level downregulates the -catenin and TCF-4 expression in caerulein-induced pancreatic inflammation