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Key weight loss results at 48 weeks by group: Response rates at 48 weeks (12 mg dose): 100% achieved greater than or equal to 5% weight loss 93% achieved greater than or equal to 10% weight loss 83% achieved greater than or equal to 15% weight loss The cardiometabolic improvements were also significant, with reductions in blood pressure, triglycerides, LDL cholesterol, HbA1c, fasting glucose, and fasting insulin across all dose groups

Clinical Study Results (TRIUMPH & TRANSCEND) Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors: Weight reduction: In phase 2 and phase 3 clinical studies, treated participants achieved approximately 24% to 28.7% weight loss over 4868 weeks

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Its formulated with Arginine and Hawthorn berry extract to promote circulation and normal blood pressure

Most GLP-1 medications start at a low dose and gradually increase every four weeks to minimize gastrointestinal side effects