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Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis

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Conditions like inflammatory bowel diseases, pernicious anemia, and chronic gastritis damage the digestive system, making 15-25% of people more likely to develop a B12 deficiency

Basal mitophagy is essential for maintaining mitochondrial homeostasis, but excessive mitophagy induces mitochondrial dysfunction, neuronal injury, and even cell death (Cherra et al., 2013