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From early peptide synthesis to uncovering GLP-1s incretin role, her impactful studies bridge fundamental science and clinical medicine
The potential mechanisms underlying the increased risk of gastric aspiration are not fully understood, and nowadays it is explained mainly by delayed gastric emptying and inhibition of gastrointestinal motor function that GLP-1-RAs exert through both central motor nuclei and vagal afferents [13, 14]
Tesofensine can have other neuroprotective effects as well
a review of the pathophysiological basis and therapeutic interventions
There are currently no Therapeutic Goods Administration-approved incretin-based medicines available on the Pharmaceutical Benefits Scheme (PBS) for obesity management (Table 7)
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