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Begin by reducing ongoing exposure, reviewing medications and alcohol, confirming liver and kidney safety, restoring adequate protein and nutrients, supporting bowel elimination and treating confirmed methylation, gut or biliary abnormalities

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Before using zonisamide, tell your health care provider about your medical history, especially if you have: kidney disease liver disease long-term diarrhea lung or breathing problems metabolic acidosis or diabetic ketoacidosis high ketone levels in your blood or urine you use insulin or other diabetes medications history of psychiatric disorders or suicidal thoughts Talk to your health care provider if you are planning to become pregnant or if pregnant or breastfeeding

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The combination of extended fasting plus AOD-9604 creates a synergistic effect that enhances fat mobilization