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Novo Nordisks Response to JAMA Study and Allegations In an emailed statement, Wegovy manufacturer Novo Nordisk countered that there were several limitations of the JAMA study design, which was not a randomized controlled trial, as reported by Reuters

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The authors characterized this pattern as quality weight loss, driven mainly by fat mass reduction with relative preservation of lean tissue

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Diabetic patients on Mounjaro see roughly 12 to 15 percent body weight loss along with strong glycemic control