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found that PF could improve the survival rate of infected mice and reduce viral titers and pulmonary fibrosis in lung tissue, and the mechanism may be related to the reduction of the virus titer in lung tissue by downregulation v3 (a type of integrin)/TGF (transforming growth factor)- 1 pathway activation is associated with reduced proinflammatory cytokine production (Yu et al., 2021)
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