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Context: Semaglutide (glp-1 receptor) is the active ingredient found in Ozempic, a Novo Nordisk drug used for the treatment of type 2 diabetes that generated global sales of approximately $13.9 billion in 2023, with the U.S

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To investigate the potential for an additive drug effect, we injected Ex(9-39) and Ex-4 reversibly to SPF and ABX mice, respectively