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Early-phase weight loss trajectories frequently do not extrapolate linearly, and many promising Phase 2 results have failed to replicate in Phase 3
It slows gastric emptying, tempers the post-meal glucagon spike, and flips satiety switches in the hindbrain and hypothalamus
Abbasihormozi et al
Swallow whole : Do not split, crush, or chew the tablet, as this affects the absorption enhancer
If you're on a 12-week protocol and week 68 used degraded medication, you've lost a month of progress you can't recover
Supporting a diverse, healthy microbiome through prebiotic and probiotic-rich foods may therefore indirectly enhance GLP-1 activity, though evidence is still emerging
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