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2021 [cited 2025 Mar 14]
April 22, 2020
Presented for research literature review only Gojkovic S et al
The 2,2-dimethyl substitution pattern on this ring occupies a lipophilic sub-pocket between TM2 and TM3 that is highly conserved in the GLP-1 receptor but differs in related class B GPCRs such as the glucagon and GIP receptors
Severe hyperglycemia requiring urgent medical attention can occur in some patients, particularly those with poorly controlled diabetes before treatment
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