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Moreover, simplified experimental paradigms often fail to capture the complex, multifactorial nature of human neurodegeneration, including chronic inflammation, metabolic dysfunction, and cumulative injury [569571]

Patients were also required to have at least one outpatient encounter within the four years prior the prescription

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(7) hyperinsulinism as an energetic response to chronic cellular injury

Without specific safety data, most clinicians would exercise considerable caution before prescribing such a combination, and many would advise against it entirely in favour of optimising single-agent therapy first