However, it is important to note that these methods currently lack robust evidence supporting their long-term efficacy, particularly in terms of sustained symptom improvement and quality of life enhancement
[1] For weight management, tirzepatide is indicated for adults with a BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity, and must be used in conjunction with a reduced-calorie diet and increased physical activity
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
At the same time, a series of studies reported that curcumin also exerts hepatoprotective activity by activating the Nrf2 signaling pathway and regulating ARE-driven antioxidant genes (Lu et al., 2015
E3S Web of Conferences, 285, 03013
Metformin blocks the stimulative effect of a high energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid acid synthase