Interestingly, gut-selective doses of sitagliptin retained the ability to improve glucose tolerance in mice with genetic ablation of DPP-4 from endothelial cells, albeit only in animals fed a chow diet and not those receiving a high-fat diet
Control samples, including both active and heat-denatured homogenates treated with the FP probe, served as positive and negative controls, respectively
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Advertisement Research ArticleAgingCell biology Open Access | 10.1172/JCI165814 1 Department of Biomedical Sciences, University of Padova, Padova, Italy
After reconstitution, it should be refrigerated for short-term stability, while freezing is recommended for extended storage