Seek immediate medical attention (call 999 or attend A&E) if you experience severe dizziness with loss of consciousness, chest pain or shortness of breath, severe persistent vomiting or diarrhoea with dehydration, neurological symptoms (slurred speech, visual disturbances, weakness), or severe abdominal pain that could indicate pancreatitis
SUSTAIN (T2D outcomes), STEP (obesity), SELECT (cardiovascular outcomes in non-diabetic obesity), and ongoing programmes in NASH/MASH, Alzheimer's, addiction neuroscience, and heart failure
The SURMOUNT-5 trial, published in 2025 in the New England Journal of Medicine, compared tirzepatide directly against a GLP-1 comparator over 72 weeks
Please note that this visit is charged at $79 and is separate from the above medication costs
Weight loss and lifestyle changes have proven to be effective in restoring menstrual regularity and reproductive function, improving hyperandrogenism, glucose and lipid metabolism, and insulin sensitivity, thus reducing cardiovascular risk in women with PCOS [18,19,20]
Author contributions Frances Chung conceived the study and wrote the study protocol
