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The result is striae distensae: those familiar bands of altered texture that creams, oils, and serums simply cannot reach because the damage lives 1.5 to 3 millimeters beneath the surface

There are no symptoms or negative effects in early stages

The FDA has specifically approved certain versions (like Wegovy and Zepbound) for chronic weight management in people without diabetes, provided they have a certain BMI (usually 30+, or 27+ with a condition like high blood pressure)

These functions protect skin cells from damage

Caltabiano R, Condorelli D, Panza S, Boitani C, Musso N, Jeek D, et al

Week-by-Week Progress: Your First Month on GLP-1 Week 1: Adjusting to GLP-1 Treatment During the first week, your body starts adapting to the medication