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Anthracycline-based FAC and FEC regimens demonstrate Level 1 evidence through Phase III trials, with GEICAM showing superior disease-free survival in 985 women and EBCTCG meta-analyses confirming 38% mortality reduction in women under 50 years, establishing it as adjuvant standard despite manageable cardiotoxicity
Am J Clin Nutr 101 , 218227, (2015)
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Sonthalia S, Jha AK, Lallas A, Jain G, Jakhar D
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