Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
Eur J Pharmacol 801:7278
Jorsal A, Kistorp C, Holmager P et al (2017) Effect of liraglutide, a glucagon-like peptide-1 analogue, on left ventricular function in stable chronic heart failure patients with and without diabetes (LIVE)a multicentre, double-blind, randomised, placebo-controlled trial
Understanding how these agents affect both metabolic and neural pathways has opened new avenues for potential BED treatment
The application of comprehensive metabolic profiling can reveal the specific lipid profiles and metabolic pathways that are most active in individual cancers thus allowing informational therapeutic approaches to be developed that take advantage of these deficiencies [261]
In a study of two psoriasis patients with diabetes, liraglutide therapy for 6 weeks resulted in rapid clinical improvement, characterized by increased circulating i NKT cells and they also demonstrated in vitro that GLP-1 induced a dose-dependent reduction of cytokine secretion from i NKT cells [77]