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Over time, it may potentially reduce the pounds

Rachot Vachathrone, MD

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The STEP-1 extension trial followed patients who had lost weight on semaglutide and then switched to placebo

However, there are certain patients for whom Wellbutrin should be avoided, including those with: A diagnosis of an eating disorder, like anorexia A seizure disorder Taking monoamine oxidase inhibitors (MAOIs) A known allergic reaction Labeling for Wellbutrin, like most antidepressants, was updated in 2005 to add a warning that it may cause rare cases of depression and comes with a risk of suicidal thoughts, especially in young adults