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Dads on compounded GLP-1 have reported losing up to 10+ lbs in the first month and seeing significant weight loss over timeall with support from licensed providers
Generally, very few studies have investigated incretin levels during childhood and adolescence
If results were minimal, redirect resources to approaches with better evidence
Biosci Biotechnol Biochem 74(9):19361939 Shuai Y, Zhang T, Mu W, Jiang B (2011) Purification and characterization of gamma-glutamyltranspeptidase from Bacillus subtilis SK11.004
The product is prepared under regulatory oversight (state pharmacy boards inspect compounding pharmacies), but the documentation standard is not as uniform as FDA-registered manufacturing
They demonstrated that pre-treatment with the GLP-1 receptor antagonist, exendin-(939), significantly reduced the entry of both GLP-1 and exendin-4 into various brain regions
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