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Moreover, oocyte mitochondria exhibit pronounced aggregation in specific cytoplasmic regions, a morphological arrangement thought to optimize energy delivery to sites critical for embryonic genome activation and early developmental program initiation [33]
Although the statistical evaluation of several of these "studies" were inadequate with some reports presenting only "clinical impressions," all investigators noted some improvement in cognitive function and positive effects of neuropsychological parameters in elderly patients with dementia subsequent to the administration of acetyl-L-carnitine [117]
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