Retatrutide is a peptide that mimics three hormones in the body: GLP-1, GIP, and glucagon Your gut releases GLP-1 after you eat, and it helps you feel full, slows how quickly food leaves your stomach, tells your pancreas to release insulin when blood sugar is high, and reduces how much sugar your liver releases into your blood
Warnings Do not exceed the recommended daily dose
Diabetes (2013) 62:23805
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More serious side effects may include severe gastrointestinal issues with the stomach, gallbladder or liver, pancreatitis, kidney failure, hypoglycemia, or depression/thoughts of suicide Zepbound (tirzepatide) causes thyroid C-cell tumors in rats, it is unknown whether it causes such tumors in humans at this time
Oxidation-sensitive residues Peptides containing cysteine, methionine, or tryptophan are particularly vulnerable to oxidation