Common B12 deficiency symptoms include fatigue, anxiety, depression, poor memory, confusion, brain fog, tingling or numbness in the extremities, zings or zapping feelings in the extremities, anemia, shortness of breath, muscle weakness, irritability, tender calves, pale complexion and more
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No responsible clinician can promise that every treatment will produce the desired outcome
[18] Systemic side effects may include headache, irritability, restlessness, depression, fatigue, or edema resulting from fluid retention
Another good reason is that some people have quite a strong adverse reaction to methylcobalamin injections
This connection has led researchers to focus on better understanding the effect of low vitamin B12 on obesity, insulin resistance, type 2 diabetes, and cardiovascular disease