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Researched applications The published preclinical literature documents the effects of BPC-157 in the following areas (mostly in animal models): Tendon and ligament healing , Achilles tendon, medial collateral ligament (MCL, the ligament on the inner side of the knee), tendinopathy models Muscle injuries , quadriceps (front thigh), gastrocnemius (calf muscle), transections and contusions Bone and joint healing , osteoarthritis models, fracture healing, periodontal tissues (around the teeth) Gastrointestinal diseases , gastric lesions caused by alcohol or NSAIDs (ibuprofen, diclofenac), colitis, IBD models (Crohns disease), fistulas Hepatoprotection , protection of the liver against toxic damage (paracetamol overdose, CCl, alcohol) Vascular healing , endothelial dysfunction, thromboses, healing of vascular anastomoses after surgery, thrombocytopenia (low platelet count) Skin wounds , acute as well as diabetic wounds, burns Nerve regeneration , peripheral (sciatic nerve crush) as well as central (cerebral ischemia models, i.e

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References for this information: Biochemistry and Cell Biology , 2019, volume 92, issue 3, pages 270-289 Biochemical Pharmacology , 2003, Volume 66, issue 8, pages 1499-1503 International Journal of Biomedical Science , 2008, volume 4, issue 2, pages 89-96 Pharmacology Review, 2010, volume 4, issue 8, pages 118-126 Antioxidants and Redox Signaling , 2013, volume 19, issue 8, pages 813-822 Nutrients , 2019, volume 11, issue 9 Biomolecules , 2015, volume 5, issue 2, pages 545-589 Aging: Oxidative Stress and Dietary Antioxidants , 2014, pages 15-22 Asian Pacific Journal of Cancer Prevention, 2014, volume 15, issue 2, pages 561-568 Clinical, Cosmetic and Investigational Dermatology , 2017, volume 10, pages 147-153 British Society for Immunology , 2020, volume 160, issue 2, pages 116-125 Harvard T.H
By 8 weeks, the mean stratum corneum hydration significantly increased from 43.7 to 51.7, along with skin elasticity in the treatment group