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At the end of each period, serial blood samples were taken to measure glucose and insulin response, leptin, triglyceride (TG), non-esterified fatty acids (NEFA) and creatine phosphokinase

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Mainstay treatments are renin-angiotensin-aldosterone system inhibitors, mineralocorticosteroid antagonists and -blockers, and, as mentioned earlier, SGLT-2 inhibitors, especially in people with comorbid diabetes

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Manufacturing companies evaluate additional factors unique to their programs

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