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The evolving medication landscape underscores the importance of individualized treatment planning, integrating both pharmacological and behavioral interventions to support long-term recovery across substance categories
A plausible explanation could be a reorientation of Lys105 towards GS resulting in a decreased stabilization of the active site thiolate as a leaving group
10.1155/2017/4517486 92 LiR.ZhouY.ZhangS.LiJ.ZhengY.FanX
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Chronic METH users exhibit significant deficits in working memory, executive function, and attention, which reflect structural and functional changes in the prefrontal cortex and hippocampus (McCann et al., 2008)
A significant decrease of these marker proteins was observed in FOXO4-DRI treated group compared with the control group (Figure 2D)
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