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The human CTR was modified to contain an N-terminal Flag tag epitope and a C-terminal 8 histidine tag epitope, each flanked by a HRV 3 C protease cleavage sites
Rather than being outcomes themselves, the peptides may be used to probe: How cells move and organize (often discussed with TB4-related actin dynamics)
All three RAMPs can interact with CTR, and this gives rise to three discrete Amy receptor phenotypes, AMY 1 R, AMY 2 R and AMY 3 R, with RAMP1, RAMP2, and RAMP3, respectively 7,8
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