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pregnant women often receive IV thiamine if needed (e.g., for hyperemesis) without issue

[9] High-dose niacin (used to treat cholesterol) lacks human safety data in pregnancy and could theoretically affect the fetus (for example, by causing hypotension or altering lipid metabolism)

[11] Because these vitamins are not long-term cumulative drugs (they dont maintain stable plasma levels like a blood pressure medication would), missing one dose is usually not critical

General Medication Guidelines - Missed Dose Instructions

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In fact, adequate B can improve pregnancy outcomes, and deficiency is common if supplementation is not given