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This inflammatory response is not only limited to the intestine, but also spreads to organs such as the liver, adipose tissue, and retina, affecting metabolic function and increasing the risk of DR and other related complications (41)
Others activate additional receptors and so are sometimes called dual-agonists
These features facilitate targeted accumulation at specific sites while reducing off-target toxicity [7]
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6 In addition, users of these medications have reported other unexpected effects such as alopecia, suicidal ideation, and aspiration, which the FDA is now investigating