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triagonism) on energy expenditure, glucose regulation, food intake, and weight loss in a well-established DIO mouse model in comparison to clinically relevant GLP1 receptor agonists [83]
However, large-scale cardiovascular (CV) outcomes trials (CVOTs) with DPP-4 inhibitors demonstrated CV safety but did not show a reduction in CV events
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Mov Disord 36:1624
PMID 11419954
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