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344 Furthermore, lactylation is implicated in the progression of musculoskeletal diseases such as osteoarthritis (OA), intervertebral disc degeneration (IDD), and tendinopathy

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Little degradation (apparent t1/2 about 10 h) of DSIP to major metabolites, tryptophan (trp) and des-trp DSIP, occurred over the time of the diffusion experiments