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avoid potent steroids on the face, flexures, or genital areas, and limit duration of use Oral antihistamines may be used regularly rather than as needed for urticarial reactions Avoidance of triggers identify and avoid potential exacerbating factors such as hot showers, tight clothing over injection sites, or known allergens When treatment modification is necessary: If reactions are recurrent or troublesome despite symptomatic management, your prescriber may consider: Delaying dose escalation by 4 weeks until symptoms improve Maintenance at a lower dose (1.7 mg) if 2.4 mg is not tolerated Switching injection sites systematically (abdomen, thigh, upper arm) to minimise localised reactions Important safety note: If you experience signs of hypersensitivity or a serious allergic reaction, stop Wegovy immediately and seek urgent medical care

PDE5 inhibitors affect blood flow peripherally

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