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Neuropharmacology 145 , 259267 (2019)
Public discourse surrounding GLP-1RAs thus remains dynamic and unsettled
Variants in GIPR (rs1800437 is the headline variant for differential GLP-1 response), FTO (appetite regulation), MC4R (satiety signaling), and TCF7L2 (insulin response) are associated with measurably different response patterns to semaglutide and tirzepatide