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But it is not impossible, especially for certain populations

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Short half-life agents (exenatide twice daily or lixisenatide) produce spikes with transient increases in plasma arGLP-1 levels, resulting in intermittent activation of the receptor and have a potent effect on gastric emptying and postprandial glycemia by reducing the rate of glucose entry into the duodenum

Shao, S

To this end, we applied a powerful scRNA-Seq tool to human islets, which will serve as a critical resource for the continued investigation of islet celltype fate changes in the pathogenesis of T2DM

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