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Abbreviations T2D: Type 2 diabetes SA: Sleep apnea GLP-1RAs: Glucagon-like peptide-1 receptor agonists LDSC: Linkage disequilibrium score regression MR: Mendelian Randomization IVW: Inverse-variance weighted GWAS: Genome-wide association study eQTL: Expression quantitative trait loci SNP: Single nucleotide polymorphism HbA1c: Glycated hemoglobin A1c OSA: Obstructive sleep apnea CSA: Central sleep apnea AHI: Apneahypopnea index NAFLD: Non-alcoholic fatty liver disease RCT: Randomized controlled trials IV: Instrumental variables References Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, et al

More concerning allergic reactions include widespread skin manifestations such as urticaria (hives), which appear as raised, itchy welts that can occur anywhere on the body

Argument-based approaches are not the most frequently used method in the validation process for PROMs, in favor of more traditional quantitative methods

Starting at investigational new drug-enabling activities, Novo Nordisk will have sole responsibility for all global development and commercialization activities

Future trials should examine both induction and maintenance therapy applications, biomarker responses, and endoscopic healing outcomes to establish clinical utility

It can be safe for certain individuals, but it must be done under strict medical supervision