Safety and translational challenges are considerable and must drive clinical application: immune stimulation carries theoretical risk as well as known risk of worsening autoimmune phenomena or inflammatory toxicities, particularly in the setting of active immunosuppression (e.g., newly diagnosed with cytotoxic therapy, on high-dose steroids)
This obviously doesnt work the same, but its similar and I actually feel 100% on this
Eating smaller, more frequent meals helps when gastric emptying slows
However, neither the innate nor the adaptive immune response is affected by the DPP-4 inhibitors being used clinically (128), and reassuringly, there is no evidence for any increased risk of infections in the pooled safety analyses (119123) or in the CV safety outcome trials (125127), in line with the view that the catalytic activity of DPP-4 is not necessary for the co-stimulatory role of CD26 in T-cell activation
If youre trying to figure out whats actually usefulnot just interestingthose differences matter more than the headline
Antioxidants 9:867 Gulcin L (2006) Antioxidant and antiradical activities of LC