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Frequency: Typically once daily, depending on the studys design

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McFadyenJDKieferJBraigDLoseff-SilverJPotempaLAEisenhardtSUet alDissociation of C-reactive protein localizes and amplifies inflammation: evidence for a direct biological role of C-reactive protein and its conformational changes

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The particles at the outer edge will be plunged into an icy environment while those deeper in will remain warm