Once aggregated, those molecules are permanently denatured
86% of adults taking Wegovy lost 5% or more weight, compared to 31% taking placebo 69% of adults taking Wegovy lost 10% or more weight, compared to 12% taking placebo 51% of adults taking Wegovy lost 15% or more weight, compared to 5% taking placebo* About 1 in 3 adults lost 46 lb or more (20% weight loss) while only 1.7% of adults on placebo experienced the same weight loss
Beyond the Scale: Key Metabolic Outcomes Weight loss is only part of the story
The authors write that there can be self-stigma or internalized stigma, which can lead to reluctance in seeking treatment
F., Larijani, B., Heshmat, R., Fakhrzadeh, H., Radjabipour, B., Toliat, T., & Raza, M
There was a small rebound, but dramatically less than the regain on placebo (9.4 kg) in the original trials