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Experimental studies have demonstrated that metformin induces a modest but functionally meaningful inhibition of mitochondrial respiratory activity, thereby constraining oxidative metabolism and limiting gluconeogenic flux [8,37,48]
Luteolin targets the toll-like receptor signaling pathway in prevention of hepatic and adipocyte fibrosis and insulin resistance in diet-induced obese mice
Lancet 406 , 26442655 (2025)
PMID 26132941
doi: 10.1128/IAI.00654-15 320 TalA.CalcagnileM.RestaS
Kawai T, Takeuchi O, Fujita T, Inoue J, Mhlradt PF, Sato S, Hoshino K, Akira S
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