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An association of treatment with GLP-1RA receptor agonists and DR was originally reported in the SUSTAIN-6 trial, which demonstrated a statistically significant increase in risk of new or worsening DR, with 3% incidence in the semaglutide group versus 1.8% in the placebo group (hazard ratio, 1.76
10.14336/AD.2019.0508 Aging Dis
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Notably, its weight-reducing efficacy in patients with common obesity is superior to that of other GLP-1 RAs [73-75]
With the addition of semaglutide, there are multiple surgical options and drugs for obesity and diabetes
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