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In contrast to chronic intact hGH treatment, AOD9604 showed no adverse effect on insulin sensitivity as assessed by euglycaemic clamp techniques

Dimet-Wiley A, Wu Q, Wiley JT, et al

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Although less common in this form than cyanocobalamine and methylcobalamine, hydroxocobalamine is also available as pills for oral or sublingual administration

common reactions include transient pain, erythema, or pruritus at the administration site, along with mild diarrhea, headache, or nausea in a minority of recipients

Standard protocols use 50100 mg/kg via oral gavage or supplemented drinking water, per institutional guidelines