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retatrutide is an incretin-based triple agonist adding GIP, GLP-1, and glucagon activity

These structural modifications give liraglutide three properties that extend its duration of action far beyond the 2-minute half-life of native GLP-1

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Common side effects from using the drugs may include dehydration and stomach issues, like nausea, diarrhea or constipation

Recognizing and addressing B12 deficiency while on semaglutide Even with injectable B12 in your compounded formulation, deficiency can still develop if your baseline levels were low, if your dose provides insufficient supplementation, or if other medications are depleting your stores faster than the weekly injection can replenish them