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In the SURPASS clinical trials, significant HbA1c reductions were observed by 40 weeks, though individual patients may achieve glycemic targets earlier, particularly at higher doses
Mansour, I
Cell Metab 2008;8:532539
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STAT signaling in inflammation
This is due to the gastric emptying delaying effect of short-acting agents, and the gastric emptying delaying effect of long-acting agents gradually decreases due to tachyphylaxis, thereby reducing the effect of postprandial glycemic control
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