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doi: 10.1186/s12933-025-02625-8 54 ZhangLAiCGuoCLiSNiuJMengXet al

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The PfGrx C88S -catalyzed deglutathionylation of monothiol roGFP2 C208S (SSG) is therefore two orders of magnitudes faster than the glutathionylation of roGFP2 C208S (SH) by PfGrx C88S (SSG) (Table 1) corresponding to the strongly shifted equilibrium towards glutathionylated PfGrx C88S and reduced roGFP2 C208S in the redox mobility shift assays (Fig

Acetyl L-Carnitine HCl is the hydrochloride salt form used for stability and solubility

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However, our included studies intervening with a dosage higher than 2000mg/d seemed to show more benefit to patients [9,10], while one subgroup [9] with 1500mg/d showed less reduction in VAS (p value not provided)