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(2022) LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist Cell Metab 34(9):1234-1247
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Semaglutide is a GLP-1 receptor agonist, which is a type of medication that mimics a natural hormone called glucagon-like peptide-1 (GLP-1)
Although its full physiological role remains unknown, enhancement of glucagon secretion and impairment of insulin secretion in response to GIP administration hinders the development of mono-GIP-directed therapies