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Semaglutide should be discontinued at least 2 months before a planned pregnancy, as weight loss is not recommended during pregnancy

Decisions on appropriate use may be made taking into consideration the glycemic parameters together with the status of CV and renal comorbidity and clinically relevant considerations, such as risk of hypoglycemia and weight gain

This makes them harder to detect through standard drug testing methods

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Many insurance companies have opted out of covering GLP-1s for weight loss only, meaning you are likely to have to pay out-of-pocket for the drugs