But there have also been concerns about safety
There's what's called cross-sectional, and then there's what's called longitudinal cross-sectional is, for example, we [00:10:00] looked at the incidents of
The companys stock has fallen about 58% over the past year as In 2023, the American Society of Anesthesiologists (ASA) issued guidelines advising patients to discontinue GLP-1 receptor agonists (GLP1-RAs) a week before surgery, citing concerns over potential operative complications, leading to delayed or rescheduled surgeries across the U.S
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Animal studies suggest GLP-1 signaling in the brain may help recalibrate sleep-wake cycles entirely independent of body weight changes, though these findings have not yet been replicated in humans (ref)