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Presented for research literature review only Halprin KM et al

Designed synthesis of 3D covalent organic frameworks

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It is also used to treat pernicious anemia, vitamin B 12 deficiency (due to low intake from food or inability to absorb due to genetic or other factors), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease

demonstrated that murine renal tubular epithelial cells become susceptible to ferroptosis with aging, marked by increased expression of the proferroptotic lipoxygenase-5 (lox-5) and reduced expression of GPX4